Of course, you can always attempt to pick up a tarantula without protective clothing. Keep in mind, however, that your risk of getting bit or otherwise injured will be higher.
Acting calmly and speaking quietly around a tarantula is the best way to be safe and avoid bites. Noise may make it feel threatened and trigger its attack reflex. Don’t poke your tarantula, or put or pour anything on it. Aggravating a tarantula may make it become aggressive. Never wave a tarantula at someone else, even as a joke. Know the signs of an impending attack: when a tarantula is threatened, it may raise its rear end and lift its front legs. Don’t blow on your tarantula, this will also annoy your tarantula and could cause it to run away or attack.
Clean the wound if you are bitten. Normally, an oral painkiller such as acetaminophen will be enough to ease discomfort. Elevating the wound site can also help relieve pain. If you see signs of infection (redness, swelling, pus, etc. ) at the bite site, you should contact a physician for an examination. You may be more likely to encounter pain or other problems if you are bitten in a sensitive area, such as your face. If you have a known allergy to tarantula bites, you should be extremely cautious when picking up a tarantula. Seek medical attention immediately if you have an allergy and are bitten, or if you experience signs of an allergic reaction, such as extreme swelling or difficulty breathing.
If you see a tarantula rearing up, get away. Always wash your hands after handling a tarantula. Wearing a face mask and gloves can help protect you from urticating hairs. [8] X Research source If urticating hairs do get on your skin, peel them of with tape and take an antihistamine, like Benadryl.